Genicular artery embolization for treatment of knee osteoarthritis pain: Systematic review and meta-analysis

ABSTRACT:

Objective

Genicular artery embolization (GAE) is a novel, minimally invasive procedure for treatment of knee osteoarthritis (OA). This meta-analysis investigated the safety and effectiveness of this procedure.

Design

Outcomes of this systematic review with meta-analysis were technical success, knee pain visual analog scale (VAS; 0–100 scale), WOMAC Total Score (0–100 scale), retreatment rate, and adverse events. Continuous outcomes were calculated as the weighted mean difference (WMD) versus baseline. Minimal clinically important difference (MCID) and substantial clinical benefit (SCB) rates were estimated in Monte Carlo simulations. Rates of total knee replacement and repeat GAE were calculated using life-table methods.

Results

In 10 groups (9 studies; 270 patie

SUBMITTER: Taslakian B 

PROVIDER: S-EPMC9971280 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature