Outcomes of Babies with Opioid Exposure (OBOE): protocol of a prospective longitudinal cohort study.

ABSTRACT:

Background

While the health, social, and economic impacts of opioid addiction on adults and their communities are well known, the impact of maternal opioid use on the fetus exposed in utero is less well understood.

Methods

This paper presents the protocol of the ACT NOW Outcomes of Babies with Opioid Exposure (OBOE) Study, a multi-site prospective longitudinal cohort study of infants with antenatal opioid exposure and unexposed controls. Study objectives are to determine the impact of antenatal opioid exposure on brain development and neurodevelopmental outcomes over the first 2 years of life and explore whether family, home, and community factors modify developmental trajectories during this critical time period.

Results

Primary outcomes related to brain development

SUBMITTER: Bann CM 

PROVIDER: S-EPMC9971338 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature