Prenatal cannabis use and its impact on offspring neuro-behavioural outcomes: A systematic review.

ABSTRACT:

Introduction

Cannabis is a widely used substance in pregnancy, yet there is a paucity of literature addressing the neuro-behavioural consequences for prenatally exposed children. Our systematic review synthesizes currently available data for the impact of prenatal cannabis use on offspring intelligence and cognitive functioning.

Methods

MEDLINE, EMBASE, PsychINFO, CINAHL, and Clinicaltrials.gov were searched. Observational studies comparing prenatal cannabis use to controls were included. Offspring neuro-behavioural outcomes were grouped in prespecified domains of (1) intelligence and (2) cognitive functioning. Random-effect models were performed for meta-analyses when at least three studies reported the same outcome. All others were summarized qualitatively. GRADE (Grading

SUBMITTER: Thompson M 

PROVIDER: S-EPMC9971580 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature