Dataset Information

Family health conditions and parental occupational status modify the relationship between pediatric-onset multiple sclerosis and parental health-related quality of life.

ABSTRACT:

Background

The health-related quality of life (HRQoL) of children with multiple sclerosis (MS) is mediated by the HRQoL of their parents. Understanding factors that modify the relationship between the child's MS diagnosis and parental HRQoL would inform interventions to improve the HRQoL of both parents and children living with MS.

Objective

We evaluated whether the association between an MS diagnosis during childhood and parental HRQoL is modified by the presence of a family health condition or low socioeconomic position (SEP).

Methods

Parents of children with MS or the transient illness, monophasic-acquired demyelinating syndromes (monoADS), were enrolled in a prospective Canadian study. Multivariable models evaluated whether the association between a child's MS diagnosis (vs. monoADS) and parental HRQoL was modified by ⩾1 family health conditions or low SEP.

Results

Two hundred seven parents and their children with MS (n = 65) or monoADS (n = 142) were included. We found a synergistic effect of an MS diagnosis and a family health condition on parental HRQoL. We also found a synergistic effect of having MS and a low SEP on parental HRQoL.

Conclusion

Parents of children with MS who have another family health condition or a low SEP are at particularly high risk for low HRQoL.

SUBMITTER: O'Mahony J

PROVIDER: S-EPMC9972245 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature

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Publications

Family health conditions and parental occupational status modify the relationship between pediatric-onset multiple sclerosis and parental health-related quality of life.

O'Mahony Julia J Banwell Brenda B Laporte Audrey A Brown Adalsteinn A Bolongaita Lady L Bar-Or Amit A Yeh E Ann EA Marrie Ruth Ann RA

Multiple sclerosis (Houndmills, Basingstoke, England) 20230119 3

<h4>Background</h4>The health-related quality of life (HRQoL) of children with multiple sclerosis (MS) is mediated by the HRQoL of their parents. Understanding factors that modify the relationship between the child's MS diagnosis and parental HRQoL would inform interventions to improve the HRQoL of both parents and children living with MS.<h4>Objective</h4>We evaluated whether the association between an MS diagnosis during childhood and parental HRQoL is modified by the presence of a family heal ...[more]

PMID: 36655814

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Dataset Information

Family health conditions and parental occupational status modify the relationship between pediatric-onset multiple sclerosis and parental health-related quality of life.

Background

Objective

Methods

Results

Conclusion

Publications

Family health conditions and parental occupational status modify the relationship between pediatric-onset multiple sclerosis and parental health-related quality of life.

Similar Datasets

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