Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia.

ABSTRACT:

Importance

The neurological substrates of visual artistic creativity (VAC) are unknown. VAC is demonstrated here to occur early in frontotemporal dementia (FTD), and multimodal neuroimaging is used to generate a novel mechanistic hypothesis involving dorsomedial occipital cortex enhancement. These findings may illuminate a novel mechanism underlying human visual creativity.

Objective

To determine the anatomical and physiological underpinnings of VAC in FTD.

Design, setting, and participants

This case-control study analyzed records of 689 patients who met research criteria for an FTD spectrum disorder between 2002 and 2019. Individuals with FTD and emergence of visual artistic creativity (VAC-FTD) were matched to 2 control groups based on demographic and clinical param

SUBMITTER: Friedberg A 

PROVIDER: S-EPMC9972248 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature