Ontology highlight
ABSTRACT:
SUBMITTER: Tellechea-Luzardo J
PROVIDER: S-EPMC9972687 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Tellechea-Luzardo Jonathan J Martín Lázaro Hèctor H Moreno López Raúl R Carbonell Pablo P
BMC bioinformatics 20230228 1
Allosteric transcription factor (aTF) based biosensors can be used to engineer genetic circuits for a wide range of applications. The literature and online databases contain hundreds of experimentally validated molecule-TF pairs; however, the knowledge is scattered and often incomplete. Additionally, compared to the number of compounds that can be produced in living systems, those with known associated TF-compound interactions are low. For these reasons, new tools that help researchers find new ...[more]