Classification of Tear Film Lipid Layer En Face Maps Obtained Using Optical Coherence Tomography and Their Correlation With Clinical Parameters.

ABSTRACT:

Purpose

The purpose of this study was to investigate the correlation between the pattern of optical coherence tomography (OCT) en face maps of the tear film lipid layer (TFLL) and lipid layer thickness (LLT), fluorescein breakup time (FBUT), and Schirmer I test values in healthy subjects.

Methods

Measurements from four clinical data sets were retrospectively analyzed, and TFLL patterns were classified into 3 categories: homogeneous (HOM), wavy (WAV), or dotted (DOT) appearance. Linear mixed model analyses were performed. Intraclass correlation coefficients and index of qualitative variation were computed to investigate interrater and intrasubject variabilities.

Results

For the LLT, a significant difference between HOM and DOT ( P < 0.001, β HOMvsDOT = -6.42 nm) and WA

SUBMITTER: Stegmann H 

PROVIDER: S-EPMC9973450 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature