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New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany.

ABSTRACT: We performed autopsies on persons in Germany who died from COVID-19 and observed higher nasopharyngeal SARS-CoV-2 viral loads for variants of concern (VOC) compared with non-VOC lineages. Pulmonary inflammation and damage appeared higher in non-VOC than VOC lineages until adjusted for vaccination status, suggesting COVID-19 vaccination may mitigate pulmonary damage.

SUBMITTER: Heinrich F

PROVIDER: S-EPMC9973696 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature

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New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany.

Heinrich Fabian F Huter Tobias T Mertens Sophie S Lange Philine P Vering Jessica J Heinemann Axel A Nörz Dominik Sebastian DS Hoffmann Armin A Aepfelbacher Martin M Ondruschka Benjamin B Krasemann Susanne S Lütgehetmann Marc M

Emerging infectious diseases 20230214 3

We performed autopsies on persons in Germany who died from COVID-19 and observed higher nasopharyngeal SARS-CoV-2 viral loads for variants of concern (VOC) compared with non-VOC lineages. Pulmonary inflammation and damage appeared higher in non-VOC than VOC lineages until adjusted for vaccination status, suggesting COVID-19 vaccination may mitigate pulmonary damage. ...[more]

PMID: 36787498

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