The effects of flow settings during high-flow nasal cannula support for adult subjects: a systematic review.

ABSTRACT:

Background

During high-flow nasal cannula (HFNC) therapy, flow plays a crucial role in the physiological effects. However, there is no consensus on the initial flow settings and subsequent titration. Thus, we aimed to systematically synthesize the effects of flows during HFNC treatment.

Methods

In this systematic review, two investigators independently searched PubMed, Embase, Web of Science, Scopus, and Cochrane for in vitro and in vivo studies investigating the effects of flows in HFNC treatment published in English before July 10, 2022. We excluded studies that investigated the pediatric population (< 18 years) or used only one flow. Two investigators independently extracted the data and assessed the risk of bias. The study protocol was prospectively registered with PROSP

SUBMITTER: Li J 

PROVIDER: S-EPMC9974062 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature