Change in four measures of physical function among older adults during lung cancer treatment: A mixed methods cohort study.

ABSTRACT:

Introduction

Functional outcomes during non-small cell lung cancer (NSCLC) treatment are critically important to older adults. Yet, data on physical function and which measures best capture functional change remain limited.

Materials and methods

This multisite, mixed methods cohort study recruited adults ≥65 years with advanced NSCLC starting systemic treatment (i.e., chemotherapy, immunotherapy, and/or targeted therapy) with non-curative intent. Participants underwent serial geriatric assessments prior to starting treatment and at one, two, four, and six months, which included the Karnofsky Performance Scale (KPS, range: 0-100%), instrumental activities of daily living (IADL, range: 0-14), European Organisation for Research and Treatment of Cancer Quality of Life Questionna

SUBMITTER: Singhal S 

PROVIDER: S-EPMC9974579 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature