Infectiousness of SARS-CoV-2 breakthrough infections and reinfections during the Omicron wave.

ABSTRACT: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infections in vaccinated individuals and reinfections in previously infected individuals have become increasingly common. Such infections highlight a broader need to understand the contribution of vaccination, including booster doses, and natural immunity to the infectiousness of individuals with SARS-CoV-2 infections, especially in high-risk populations with intense transmission, such as in prisons. Here we show that both vaccine-derived and naturally acquired immunity independently reduce the infectiousness of persons with Omicron variant SARS-CoV-2 infections in a prison setting. Analyzing SARS-CoV-2 surveillance data from December 2021 to May 2022 across 35 California state prisons with a predominately male popul

SUBMITTER: Tan ST 

PROVIDER: S-EPMC9974584 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature