Sentinel Node Procedure to Select Clinically Localized Prostate Cancer Patients with Occult Nodal Metastases for Whole Pelvis Radiotherapy.

ABSTRACT:

Background

Accurate identification of men who harbor nodal metastases is necessary to select patients who most likely benefit from whole pelvis radiotherapy (WPRT). Limited sensitivity of diagnostic imaging approaches for the detection of nodal micrometastases has led to the exploration of the sentinel lymph node biopsy (SLNB).

Objective

To evaluate whether SLNB can be used as a tool to select pathologically node-positive patients who likely benefit from WPRT.

Design setting and participants

We included 528 clinically node-negative primary prostate cancer (PCa) patients with an estimated nodal risk of >5% treated between 2007 and 2018.

Intervention

A total of 267 patients were directly treated with prostate-only radiotherapy (PORT; non-SLNB group), while 261 pa

SUBMITTER: de Barros HA 

PROVIDER: S-EPMC9975002 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature