Tricuspid-regurgitation-mediated flow-driven right-to-left cardiac shunting caused systemic hypoxemia in a patient with patent foramen ovale without elevated right atrial pressure

ABSTRACT: The prevalence of patent foramen ovale (PFO) is 20–25% among adults. The role of right-to-left shunting through the PFO in systemic hypoxemia remains poorly understood. Right-to-left shunting through the PFO can occur either due to elevated right atrial pressure (pressure-driven) or directed venous flow toward the PFO (flow-driven). Herein, we report a rare case of flow-driven right-to-left shunting via the PFO in a patient with traumatic tricuspid regurgitation. A 45-year-old Chinese woman was admitted due to progressive dyspnea for 3 years, presenting with cyanosis and digital clubbing. She was hypoxic, with an oxygen saturation of 83% on room air, and arterial blood gas showed an oxygen tension of 53 mmHg. Echocardiography showed severe tricuspid regurgitation with ruptured chordae tend

SUBMITTER: Teng P 

PROVIDER: S-EPMC9975270 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature