Present and future perspectives in early diagnosis and monitoring for progressive fibrosing interstitial lung diseases.

ABSTRACT: Progressive fibrosing interstitial lung diseases (PF-ILDs) represent a group of conditions of both known and unknown origin which continue to worsen despite standard treatments, leading to respiratory failure and early mortality. Given the potential to slow down progression by initiating antifibrotic therapies where appropriate, there is ample opportunity to implement innovative strategies for early diagnosis and monitoring with the goal of improving clinical outcomes. Early diagnosis can be facilitated by standardizing ILD multidisciplinary team (MDT) discussions, implementing machine learning algorithms for chest computed-tomography quantitative analysis and novel magnetic-resonance imaging techniques, as well as measuring blood biomarker signatures and genetic testing for telomere lengt

SUBMITTER: Stanel SC 

PROVIDER: S-EPMC9975385 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature