The relationship between single nucleotide polymorphisms and skin cancer susceptibility: A systematic review and network meta-analysis.

ABSTRACT:

Background

Single nucleotide polymorphisms (SNPs) interfere with the function of certain genes and thus may influence the probability of skin cancer. The correlation between SNPs and skin cancer (SC) lacks statistical power, however. Therefore, the purpose of this study was to identify the gene polymorphisms involved in skin cancer susceptibility using network meta-analysis and to determine the relationship between SNPs and SC risk.

Methods

PubMed, Embase, and Web of Science were searched for articles including "SNP" and different types of SC as keywords between January 2005 and May 2022. The Newcastle-Ottawa Scale was used to assess bias judgments. The odds ratio (ORs) and their 95% confidence intervals (CIs) were determined to estimate heterogeneity within and betwe

SUBMITTER: Zhang L 

PROVIDER: S-EPMC9975575 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature