Systemic inflammation indicators and risk of incident arrhythmias in 478,524 individuals: evidence from the UK Biobank cohort.

ABSTRACT:

Background

The role of systemic inflammation in promoting cardiovascular diseases has attracted attention, but its correlation with various arrhythmias remains to be clarified. We aimed to comprehensively assess the association between various indicators of systemic inflammation and atrial fibrillation/flutter (AF), ventricular arrhythmia (VA), and bradyarrhythmia in the UK Biobank cohort.

Methods

After excluding ineligible participants, a total of 478,524 eligible individuals (46.75% male, aged 40-69 years) were enrolled in the study to assess the association between systemic inflammatory indicators and each type of arrhythmia.

Results

After covariates were fully adjusted, CRP levels were found to have an essentially linear positive correlation with the risk of vario

SUBMITTER: Yang X 

PROVIDER: S-EPMC9976398 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature