Brain fatty acid and transcriptome profiles of pig fed diets with different levels of soybean oil.

ABSTRACT:

Background

The high similarity in anatomical and neurophysiological processes between pigs and humans make pigs an excellent model for metabolic diseases and neurological disorders. Lipids are essential for brain structure and function, and the polyunsaturated fatty acids (PUFA) have anti-inflammatory and positive effects against cognitive dysfunction in neurodegenerative diseases. Nutrigenomics studies involving pigs and fatty acids (FA) may help us in better understanding important biological processes. In this study, the main goal was to evaluate the effect of different levels of dietary soybean oil on the lipid profile and transcriptome in pigs' brain tissue.

Results

Thirty-six male Large White pigs were used in a 98-day study using two experimental diets corn-soybean me

SUBMITTER: da Silva BP 

PROVIDER: S-EPMC9976441 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature