About the dark corners in the gene function space of Escherichia coli remaining without illumination by scientific literature.

ABSTRACT:

Background

Although Escherichia coli (E. coli) is the most studied prokaryote organism in the history of life sciences, many molecular mechanisms and gene functions encoded in its genome remain to be discovered. This work aims at quantifying the illumination of the E. coli gene function space by the scientific literature and how close we are towards the goal of a complete list of E. coli gene functions.

Results

The scientific literature about E. coli protein-coding genes has been mapped onto the genome via the mentioning of names for genomic regions in scientific articles both for the case of the strain K-12 MG1655 as well as for the 95%-threshold softcore genome of 1324 E. coli strains with known complete genome. The article match was quantified with the ratio of a given ge

SUBMITTER: Tantoso E 

PROVIDER: S-EPMC9976479 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature