Efficacy of epinephrine in local infiltration analgesia on pain relief and opioid consumption following total knee arthroplasty: a randomized controlled trial.

ABSTRACT:

Background and purpose

Local infiltration analgesia (LIA) is one of the effective regimens to reduce pain after total knee arthroplasty (TKA). Epinephrine is a commonly used sympathetic adjunct in LIA. It is expected to enhance the intensity and extend the duration of LIA. The primary aim of the study was to evaluate the efficacy of epinephrine on postoperative pain control after primary TKA.

Patients and methods

A total of 80 patients who underwent primary TKA were randomized into an epinephrine (EN) and a control (C) group. Postoperative visual analogue pain score (VAPS) and morphine consumption were recorded every 6 hours until 48 hours after operation. The VAPS 6-48 hours were compared using repeated measure statistics. The range of motion (ROM) on discharge and complica

SUBMITTER: Chareancholvanich K 

PROVIDER: S-EPMC9976710 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature