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Protocol Development and Initial Experience With Intravenous Sotalol Loading for Atrial Arrhythmias.


ABSTRACT:

Background

Oral sotalol is a class III antiarrhythmic commonly used for the maintenance of sinus rhythm in patients with atrial fibrillation (AF). Recently, the Food and Drug Administration (FDA) approved the use of IV sotalol loading, based primarily on modeling data for the infusion. We aimed to describe a protocol and experience with IV sotalol loading for elective treatment of adult patients with AF and atrial flutter (AFL).

Methods

We present our institutional protocol and retrospective review of initial patients treated with IV sotalol for AF/AFL at the University of Utah Hospital between September 2020 and April 2021.

Results

Eleven patients received IV sotalol for initial loading or dose escalation. All patients were male, aged 56-88 years (median 69). Mean QT

SUBMITTER: Feuerborn ML 

PROVIDER: S-EPMC9977272 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature