Sulcal depth in prefrontal cortex: a novel predictor of working memory performance.

ABSTRACT: The neuroanatomical changes that underpin cognitive development are of major interest in neuroscience. Of the many aspects of neuroanatomy to consider, tertiary sulci are particularly attractive as they emerge last in gestation, show a protracted development after birth, and are either human- or hominoid-specific. Thus, they are ideal targets for exploring morphological-cognitive relationships with cognitive skills that also show protracted development such as working memory (WM). Yet, the relationship between sulcal morphology and WM is unknown-either in development or more generally. To fill this gap, we adopted a data-driven approach with cross-validation to examine the relationship between sulcal depth in lateral prefrontal cortex (LPFC) and verbal WM in 60 children and adolescents bet

SUBMITTER: Yao JK 

PROVIDER: S-EPMC9977365 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature