Ontology highlight
ABSTRACT:
SUBMITTER: Dimopoulos K
PROVIDER: S-EPMC9977420 | biostudies-literature | 2023 Jan
REPOSITORIES: biostudies-literature
Dimopoulos Konstantinos K Constantine Andrew A Clift Paul P Condliffe Robin R Moledina Shahin S Jansen Katrijn K Inuzuka Ryo R Veldtman Gruschen R GR Cua Clifford L CL Tay Edgar Lik Wui ELW Opotowsky Alexander R AR Giannakoulas George G Alonso-Gonzalez Rafael R Cordina Rachael R Capone George G Namuyonga Judith J Scott Charmaine H CH D'Alto Michele M Gamero Francisco J FJ Chicoine Brian B Gu Hong H Limsuwan Alisa A Majekodunmi Tosin T Budts Werner W Coghlan Gerry G Broberg Craig S CS
Circulation 20230130 5
Cardiovascular disease is a leading cause of morbidity and mortality in individuals with Down syndrome. Congenital heart disease is the most common cardiovascular condition in this group, present in up to 50% of people with Down syndrome and contributing to poor outcomes. Additional factors contributing to cardiovascular outcomes include pulmonary hypertension; coexistent pulmonary, endocrine, and metabolic diseases; and risk factors for atherosclerotic disease. Moreover, disparities in the card ...[more]