Maternal hemoglobin concentrations across pregnancy and child health and development from birth through 6-7 years.

ABSTRACT:

Background

The role of changes in maternal hemoglobin (Hb) across pregnancy on child health and development (CHD) remains unclear.

Objective

We examined the association between maternal Hb trajectories and CHD outcomes: (a) birth outcomes (birth weight, length, gestational age, preterm, and small for gestational age); (b) child Hb at 3, 6, 12, and 24 months; and (c) motor and mental development at 12 and 24 months and cognitive functioning at age 6-7 years.

Methods

We used data from a randomized controlled trial (PRECONCEPT) conducted in Vietnam (N = 1,175 women enrolled during preconception with offspring follow-up through 6-7 years). Maternal Hb trajectories were developed using latent class analysis with Hb data at preconception, early (≤20 weeks), mid (21-2

SUBMITTER: Young MF 

PROVIDER: S-EPMC9978095 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature