The precision of ROTEM EXTEM is decreased in hypocoagulable blood: a prospective observational study.

ABSTRACT:

Background

The use of viscoelastic tests is becoming increasingly popular. There is a paucity of validation of the reproducibility of varying coagulation states. Therefore, we aimed to study the coefficient of variation (CV) for the ROTEM EXTEM parameters clotting time (CT), clot formation time (CFT), alpha-angle and maximum clot firmness (MCF) in blood with varying degrees of coagulation strength. The hypothesis was that CV increases in states of hypocoagulability.

Methods

Critically ill patients and patients subjected to neurosurgery at a university hospital during three separate periods were included. Each blood sample was tested in eight parallel channels, yielding the CVs for the tested variables. In 25 patients, the blood samples were analysed both at baseline and afte

SUBMITTER: Sunnersjo L 

PROVIDER: S-EPMC9978281 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature