Assessing thermal adaptation of a global sample of Aspergillus fumigatus: Implications for climate change effects.

ABSTRACT: Aspergillus fumigatus is a common environmental mold and a major cause of opportunistic infections in humans. It's distributed among many ecological niches across the globe. A major virulence factor of A. fumigatus is its ability to grow at high temperature. However, at present, little is known about variations among strains in their growth at different temperatures and how their geographic origins may impact such variations. In this study, we analyzed 89 strains from 12 countries (Cameroon, Canada, China, Costa Rica, France, India, Iceland, Ireland, New Zealand, Peru, Saudi Arabia, and USA) representing diverse geographic locations and temperature environments. Each strain was grown at four temperatures and genotyped at nine microsatellite loci. Our analyses revealed a range

SUBMITTER: Korfanty G 

PROVIDER: S-EPMC9978374 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature