The association between distal symmetric polyneuropathy in diabetes with all-cause mortality - a meta-analysis.

ABSTRACT:

Background

Distal symmetric polyneuropathy (DSPN) is a common microvascular complication of both type 1 and 2 diabetes with substantial morbidity burden and reduced quality of life. Its association with mortality is equivocal.

Purpose

To describe the association between DSPN and all-cause mortality in people with diabetes and further stratify by the type of diabetes based on a meta-analysis of published observational studies.

Data sources

We searched Medline from inception to May 2021.

Study selection

Original data were collected from case-control and cohort studies that reported on diabetes and DSPN status at baseline and all-cause mortality during follow-up.

Data extraction

was completed by diabetes specialists with clinical experience in neuropathy as

SUBMITTER: Vagi OE 

PROVIDER: S-EPMC9978416 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature