Artificial intelligence-based prediction of overall survival in metastatic renal cell carcinoma.

ABSTRACT:

Background and objectives

Investigations of the prognosis are vital for better patient management and decision-making in patients with advanced metastatic renal cell carcinoma (mRCC). The purpose of this study is to evaluate the capacity of emerging Artificial Intelligence (AI) technologies to predict three- and five-year overall survival (OS) for mRCC patients starting their first-line of systemic treatment.

Patients and methods

The retrospective study included 322 Italian patients with mRCC who underwent systemic treatment between 2004 and 2019. Statistical analysis included the univariate and multivariate Cox proportional-hazard model and the Kaplan-Meier analysis for the prognostic factors' investigation. The patients were split into a training cohort to establish the pr

SUBMITTER: Barkan E 

PROVIDER: S-EPMC9978529 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature