Development and Validation of a Scoring System for Hemorrhage Risk in Brain Arteriovenous Malformations.

ABSTRACT:

Importance

The dilemma between natural rupture risk and adverse outcomes of intervention is of major concern for patients with unruptured arteriovenous malformations (AVMs). The existing risk score for AVM rupture includes factors that are controversial and lacks prospective validation.

Objective

To develop and robustly validate a reliable scoring system to predict the rupture risk of AVMs.

Design, setting, and participants

This prognostic study developed a prediction model derived from a single-center cohort (derivation cohort) and validated in a multicenter external cohort (multicenter external validation cohort) and a cohort of patients receiving conservative treatment management (conservative treatment validation cohort). Patients were recruited from a nationwide

SUBMITTER: Chen Y 

PROVIDER: S-EPMC9978947 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature