Type 2 diabetes mellitus characteristics affect hepatocellular carcinoma development in chronic hepatitis B patients with cirrhosis.

ABSTRACT:

Background

Type 2 diabetes mellitus (T2DM) has been shown to be correlated with hepatocellular carcinoma (HCC) development. However, further investigation is needed to understand how T2DM characteristics affect the prognosis of chronic hepatitis B (CHB) patients.

Aim

To assess the effect of T2DM on CHB patients with cirrhosis and to determine the risk factors for HCC development.

Methods

Among the 412 CHB patients with cirrhosis enrolled in this study, there were 196 with T2DM. The patients in the T2DM group were compared to the remaining 216 patients without T2DM (non-T2DM group). Clinical characteristics and outcomes of the two groups were reviewed and compared.

Results

T2DM was significantly related to hepatocarcinogenesis in this study (P = 0.002). T

SUBMITTER: Li MY 

PROVIDER: S-EPMC9979280 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature