Association between seropositivity for toxocariasis and cognitive functioning in older adults: an analysis of cross-sectional data from the US National Health and Nutrition Examination Survey (NHANES), 2011-2014.

ABSTRACT:

Objectives

This study sought to examine the relationship between seropositivity for toxocariasis and cognitive functioning in a nationally representative sample of US older adults.

Design

A cross-sectional study.

Setting

National Health and Nutrition Examination Survey (NHANES) data collection took place in the US at participants' homes and mobile examination centres with specialised equipment.

Participants

The study population consisted of 3188 community-dwelling US older adults aged 60 and above from the NHANES 2011 to 2014.

Outcome measures

IgG antibody against Toxocara spp was tested by a Luminex assay using recombinant rTc-CTL-1 antigen. A value >23.1 mean fluorescence intensity (MFI) indicated positive for toxocariasis and a value ≤23.1 MFI

SUBMITTER: Song G 

PROVIDER: S-EPMC9980365 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature