Assessment of low immunoglobulin levels and clinical manifestations in patients with mastocytosis.

ABSTRACT:

Background

Patients with a low IgG level alone or with low IgA or IgM levels have been reported to be susceptible to respiratory tract infections and recurrent sinusitis. Patients diagnosed with CVID have a higher prevalence of autoimmune diseases and lymphoid malignancies. Mastocytosis is a myeloproliferative disease, not typically associated with autoimmune disease or frequent infections.

Objective

We sought to determine the distribution of immunoglobulins in children and adults with mastocytosis. Evaluate the impact of low immunoglobulins on the clinical management of patients with mastocytosis.

Methods

We performed a 10-year retrospective analysis on 320 adult and pediatric patients with mastocytosis for immunoglobulins using an electronic medical query. We identi

SUBMITTER: Makovoz A 

PROVIDER: S-EPMC9980822 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature