Association between Sports Participation, Factor VIII Levels and Bleeding in Hemophilia A.

ABSTRACT:

Background

 Little is known on how sports participation affects bleeding risk in hemophilia. This study aimed to examine associations between sports participation, factor VIII (FVIII) levels and bleeding in persons with hemophilia A.

Methods

 In this observational, prospective, single-center study, persons with hemophilia A who regularly participated in sports were followed for 12 months. The associations of patient characteristics, FVIII levels, and type/frequency of sports participation with bleeding were analyzed by repeated time-to-event modelling.

Results

 One hundred and twelve persons (median age: 24 years [interquartile range:16-34], 49% severe, 49% on prophylaxis) were included. During follow-up, 70 bleeds of which 20 sports-induced were observed. FVIII level

SUBMITTER: Bukkems LH 

PROVIDER: S-EPMC9981275 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature