Identifying hepatic genes regulating the ovine response to gastrointestinal nematodes using RNA-Sequencing.

ABSTRACT: Gastrointestinal nematode (GIN) infections are considered the most important disease of grazing sheep and due to increasing anthelmintic resistance, chemical control alone is inadequate. Resistance to Gastrointestinal nematode infection is a heritable trait, and through natural selection many sheep breeds have higher resistance. Studying the transcriptome from GIN-exposed and GIN-unexposed sheep using RNA-Sequencing technology can provide measurements of transcript levels associated with the host response to Gastrointestinal nematode infection, and these transcripts may harbor genetic markers that can be used in selective breeding programs to enhance disease resistance. The objective of this study was to compare liver transcriptomes of sheep naturally exposed to Gastrointestinal nem

SUBMITTER: Dixon S 

PROVIDER: S-EPMC9981634 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature