Allelic variation of TaWD40-4B.1 contributes to drought tolerance by modulating catalase activity in wheat.

ABSTRACT: Drought drastically restricts wheat production, so to dissect allelic variations of drought tolerant genes without imposing trade-offs between tolerance and yield is essential to cope with the circumstance. Here, we identify a drought tolerant WD40 protein encoding gene TaWD40-4B.1 of wheat via the genome-wide association study. The full-length allele TaWD40-4B.1^C but not the truncated allele TaWD40-4B.1^T possessing a nonsense nucleotide variation enhances drought tolerance and grain yield of wheat under drought. TaWD40-4B.1^C interacts with canonical catalases, promotes their oligomerization and activities, and reduces H₂O₂ levels under drought. The knock-down of catalase genes erases the role of TaWD40-4B.1^C in drought tole

SUBMITTER: Tian G 

PROVIDER: S-EPMC9981739 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature