An innovative wireless electrochemical card sensor for field-deployable diagnostics of Hepatitis B surface antigen.

ABSTRACT: A wireless-based detection utilizing an innovative electrochemical card (eCard) sensor controlled by a smartphone was developed for targeting Hepatitis B surface antigen (HBsAg). A simple label-free electrochemical platform allows a convenient operation for point-of-care diagnosis. A disposable screen-printed carbon electrode was modified straightforwardly layer-by-layer with chitosan followed by glutaraldehyde, allowing a simple but effective, reproducible, and stable method for covalently immobilizing antibodies. The modification and immobilization processes were verified by electrochemical impedance spectroscopy and cyclic voltammetry. The smartphone-based eCard sensor was used to quantify HBsAg by measuring the change in current response of the [Fe(CN)₆]^3-/4- redo

SUBMITTER: Teengam P 

PROVIDER: S-EPMC9981757 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature