Cancer-associated fibroblasts, and clinicopathological characteristics and prognosis of gastric cancer: A systematic review and meta-analysis.

ABSTRACT:

Objective

To systematically evaluate the relationship between cancer-associated fibroblasts (CAFs) and clinicopathological characteristics and prognosis of gastric cancer, so as to provide new directions and clinical evidence for the diagnosis and treatment of this disease.

Methods

We searched PubMed, Embase, Web of Science, and The Cochrane Library to identify studies on the correlation between tumor-associated fibroblasts and the diagnosis and prognosis of gastric cancer. Two researchers screened the literature independently to extract data, evaluated the quality of the included studies, and used the Review Manager 5.4 software to perform a meta-analysis.

Results

A total of 14 studies involving a total of 2,703 patients were included. The meta-analysis results showe

SUBMITTER: Wei J 

PROVIDER: S-EPMC9981791 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature