Hyperbaric oxygen therapy for local late radiation toxicity in breast cancer patients: A systematic review.

ABSTRACT:

Purpose

This systematic review aims to provide an overview of the literature on the effect of hyperbaric oxygen therapy (HBOT) on symptoms of local late radiation toxicity (LRT) in patients treated for breast cancer.

Methods

A systematic search was performed in September 2021. All studies with a sample size of ≥10 patients reporting the effect of HBOT for symptoms of LRT after radiotherapy of the breast and/or chest wall were included. The ROBINS-I tool was used for critical appraisal of methodological quality. The toxicity outcomes pain, fibrosis, lymphedema, necrosis/skin problems, arm and shoulder mobility, and breast and arm symptoms were evaluated.

Results

Nine studies concerning a total of 1308 patients were included in this review. Except for one study, sample

SUBMITTER: Meier EL 

PROVIDER: S-EPMC9982272 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature