Continuous Glucose Monitoring Enabled by Fluorescent Nanodiamond Boronic Hydrogel.

ABSTRACT: Continuous monitoring of glucose allows diabetic patients to better maintain blood glucose level by altering insulin dosage or diet according to prevailing glucose values and thus to prevent potential hyperglycemia and hypoglycemia. However, current continuous glucose monitoring (CGM) relies mostly on enzyme electrodes or micro-dialysis probes, which suffer from insufficient stability, susceptibility to corrosion of electrodes, weak or inconsistent correlation, and inevitable interference. A fluorescence-based glucose sensor in the skin will likely be more stable, have improved sensitivity, and can resolve the issues of electrochemical interference from the tissue. This study develops a fluorescent nanodiamond boronic hydrogel system in porous microneedles for CGM. Fluorescent nanodiamond

SUBMITTER: Zhang J 

PROVIDER: S-EPMC9982560 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature