Development of novel biliary metal stent with coil-spring structure and its application in vivo swine biliary stricture model.

ABSTRACT:

Background

As of date, endoscopic biliary stenting with plastic stent (PS) and self-expandable metal stent (SEMS) have been widely used for the palliation of biliary tract strictures. However, these two stents have several limitations regarding the management of biliary strictures caused by intrahepatic and hilar cholangiocarcinoma. PS has short patency and also risks bile duct injury and bowel perforation. SEMS is difficult to revise when occluded by tumor overgrowth. To compensate for such shortcomings, we developed a novel biliary metal stent with coil-spring structure. The aim of this study was to investigate the feasibility and efficacy of the novel stent in a swine model.

Methods

The biliary stricture model was prepared in six mini-pigs using endobiliary radiofrequency

SUBMITTER: Cho IR 

PROVIDER: S-EPMC9982730 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature