Atypical functional hierarchy contributed to the tinnitus symptoms in patients with vestibular schwannoma.

ABSTRACT:

Objective

Tinnitus is frequently found in patients with vestibular schwannoma (VS), but its underlying mechanisms are currently unclear.

Methods

Both preoperative (VS _pre ) and postoperative (VS _post ) functional MR images were collected from 32 patients with unilateral VS and matched healthy controls (HCs). Connectome gradients were generated for the identification of altered regions and perturbed gradient distances. Tinnitus measurements were conducted for predictive analysis with neuroimaging-genetic integration analysis.

Results

There were 56.25% of preoperative patients and 65.63% of postoperative patients suffering from ipsilateral tinnitus, respectively. No relevant factors were identified including basic demographics info, h

SUBMITTER: Lin J 

PROVIDER: S-EPMC9982843 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature