Predictive value of pigment epithelial detachment markers for visual acuity outcomes in neovascular age-related macular degeneration.

ABSTRACT:

Background

To determine the predictive value of quantitative morphological parameters for pigment epithelial detachment (PED) of neovascular age-related macular degeneration (nAMD) patients.

Methods

One eye from each of 159 patients with nAMD were studied. Polypoidal choroidal vasculopathy (PCV) group included 77 eyes, and non-PCV group 82. Patients received conbercept 0.05 ml (0.5 mg) in a 3 + ProReNata (PRN) treatment regimen. Correlations between retinal morphologic parameters at baseline and best-corrected visual acuity (BCVA) gain at 3 or 12 months after treatment (structure-function correlations) were assessed. Optical coherence tomography (OCT) scans were used to assess retinal morphologic features including intraretinal cystoid fluid (IRC), subretinal fluid (SRF), PE

SUBMITTER: Shu Y 

PROVIDER: S-EPMC9983272 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature