Habituation or sensitization of brain response to food cues: Temporal dynamic analysis in an functional magnetic resonance imaging study

ABSTRACT:

Introduction

In the modern obesogenic environment, heightened reactivity to food-associated cues plays a major role in overconsumption by evoking appetitive responses. Accordingly, functional magnetic resonance imaging (fMRI) studies have implicated regions of the salience and rewards processing in this dysfunctional food cue-reactivity, but the temporal dynamics of brain activation (sensitization or habituation over time) remain poorly understood.

Methods

Forty-nine obese or overweight adults were scanned in a single fMRI session to examine brain activation during the performance of a food cue-reactivity task. A general linear model (GLM) was used to validate the activation pattern of food cue reactivity in food > neutral contrast. The linear mixed effect models were use

SUBMITTER: Ghobadi-Azbari P 

PROVIDER: S-EPMC9983367 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature