A time-series analysis of blood-based biomarkers within a 25-year longitudinal dolphin cohort.

ABSTRACT: Causal interactions and correlations between clinically-relevant biomarkers are important to understand, both for informing potential medical interventions as well as predicting the likely health trajectory of any individual as they age. These interactions and correlations can be hard to establish in humans, due to the difficulties of routine sampling and controlling for individual differences (e.g., diet, socio-economic status, medication). Because bottlenose dolphins are long-lived mammals that exhibit several age-related phenomena similar to humans, we analyzed data from a well controlled 25-year longitudinal cohort of 144 dolphins. The data from this study has been reported on earlier, and consists of 44 clinically relevant biomarkers. This time-series data exhibits three starkly diffe

SUBMITTER: Rangan AV 

PROVIDER: S-EPMC9983899 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature