Anti-angiogenic therapy for advanced primary pulmonary lymphoepithelioma-like carcinoma: a retrospective multicenter study.

ABSTRACT:

Purpose

Primary pulmonary lympho-epithelioma-like carcinoma (PPLELC) is a rare subtype of primary non-small cell lung cancer (NSCLC). Currently, there is still lack of research data on anti-angiogenic therapy of advanced PPLELC. The purpose of this study was to investigate the efficacy and safety of anti-angiogenic therapy combined with chemotherapy compared with traditional chemotherapy for these patients.

Methods

Advanced PPLELC patients admitted to six grade A hospitals from January 2013 to January 2021 were selected. The patients received anti-angiogenic therapy combined with chemotherapy (AT group) or chemotherapy (CT group) alone.

Results

A total of 65 patients were included in this study, including 31 patients in the AT group treated with anti-angiogenic therap

SUBMITTER: Bao H 

PROVIDER: S-EPMC9984323 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature