Machine learning identifies straightforward early warning rules for human Puumala hantavirus outbreaks.

ABSTRACT: Human Puumala virus (PUUV) infections in Germany fluctuate multi-annually, following fluctuations of the bank vole population size. We applied a transformation to the annual incidence values and established a heuristic method to develop a straightforward robust model for the binary human infection risk at the district level. The classification model was powered by a machine-learning algorithm and achieved 85% sensitivity and 71% precision, despite using only three weather parameters from the previous years as inputs, namely the soil temperature in April of two years before and in September of the previous year, and the sunshine duration in September of two years before. Moreover, we introduced the PUUV Outbreak Index that quantifies the spatial synchrony of local PUUV-outbreaks, and applie

SUBMITTER: Kazasidis O 

PROVIDER: S-EPMC9984366 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature