Safe use of PHI6 IN the experimental studies.

ABSTRACT: Surrogate viruses theoretically provide an opportunity to study the viral spread in an indoor environment, a highly needed understanding during the pandemic, in a safe manner to humans and the environment. However, the safety of surrogate viruses for humans as an aerosol at high concentrations has not been established. In this study, Phi6 surrogate was aerosolized at high concentration (Particulate matter_2.5: ∼1018 μg m^-3) in the studied indoor space. Participants were closely followed for any symptoms. We measured the bacterial endotoxin concentration of the virus solution used for aerosolization as well as the concentration in the room air containing the aerosolized viruses. In addition, we measured how the bacterial endotoxin concentration of the sample was affecte

SUBMITTER: Sanmark E 

PROVIDER: S-EPMC9984441 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature