Site-specific factors associated with clinical trial recruitment efficiency in general practice settings: a comparative descriptive analysis.

ABSTRACT:

Background

Recruitment of participants is crucial to the success of randomised control trials (RCTs) but can be challenging and expensive. Current research on trial efficiency is often focused at the patient-level with an emphasis on effective recruitment strategies. Less is known about selection of study sites to optimise recruitment. We examine site-level factors that are associated with patient recruitment and cost efficiency using data from an RCT conducted across 25 general practices (GP) in Victoria, Australia.

Methods

Data on number of participants screened, excluded, eligible, recruited, and randomised from each study site were extracted from a clinical trial. Details regarding site characteristics, recruitment practices, and staff time commitment were collected usin

SUBMITTER: Tew M 

PROVIDER: S-EPMC9985191 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature