Immune markers and microbial factors are related with periodontitis severity in people with HIV.

ABSTRACT:

Objective

The objective of the study is to assess systemic immune markers and microbial factors related to periodontitis severity in people living with HIV.

Methods

Eighty people living with HIV (PLWH), who exhibited in the last two viral load measurements < 40 copies/mL, underwent full-mouth periodontal examinations and sub-gingival plaque sampling. Periodontitis was classified according to the CDC-AAP case definition. Inflammation, immune-activation, and immunosenescence markers were assessed, microbiological analyses were performed, and oral care routines and HIV characteristics were noted.

Results

From our group of PLWH, 42.5% and 57.5% suffered from moderate and severe periodontitis, respectively. Oral care habits did not differ between PLWH with moderate and sev

SUBMITTER: Groenewegen H 

PROVIDER: S-EPMC9985580 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature