Clinical advances in epigenetic therapies for lymphoma.

ABSTRACT:

Background

Advances in understanding of cancer biology, genomics, epigenomics, and immunology have resulted in development of several therapeutic options that expand cancer care beyond traditional chemotherapy or radiotherapy, including individualized treatment strategies, novel treatments based on monotherapies or combination therapy to reduce toxicities, and implementation of strategies for overcoming resistance to anticancer therapy.

Results

This review covers the latest applications of epigenetic therapies for treatment of B cell, T cell, and Hodgkin lymphomas, highlighting key clinical trial results with monotherapies and combination therapies from the main classes of epigenetic therapies, including inhibitors of DNA methyltransferases, protein arginine methyltransferas

SUBMITTER: Rosenthal AC 

PROVIDER: S-EPMC9985856 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature