Crystal structure and characterization of the sulfamethazine-piperidine salt.

ABSTRACT: Sulfamethazine [N¹-(4,6-dimethylpyrimidin-2-yl)sulfanilamide] is an antimicrobial drug that possesses functional groups capable of acting as hydrogen-bond donors and acceptors, which make it a suitable supramolecular building block for the formation of cocrystals and salts. We report here the crystal structure and solid-state characterization of the 1:1 salt piperidinium sulfamethazinate (PPD⁺·SUL^-, C₅H₁₂N⁺·C₁₂H₁₃N₄O₂S^-) (I). The salt was obtained by the solvent-assisted grinding method and was characterized by IR spectroscopy, powder X-ray diffraction, solid-state ¹³C NMR spectroscopy and thermal analysis [differential scanning calorimetry (DSC) and thermogra

SUBMITTER: Gonzalez-Gonzalez JS 

PROVIDER: S-EPMC9985947 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature